RENEB biodosimetry intercomparison analyzing translocations by FISH
نویسندگان
چکیده
منابع مشابه
The first gamma-H2AX biodosimetry intercomparison exercise of the developing European biodosimetry network RENEB.
In the event of a mass casualty radiation incident, the gamma-H2AX foci assay could be a useful tool to estimate radiation doses received by individuals. The rapid processing time of blood samples of just a few hours and the potential for batch processing, enabling high throughput, make the assay ideal for early triage categorisation to separate the 'worried well' from the low and critically ex...
متن کاملRealising the European Network of Biodosimetry (RENEB).
In Europe, a network for biological dosimetry has been created to strengthen the emergency preparedness and response capabilities in case of a large-scale nuclear accident or radiological emergency. Through the RENEB (Realising the European Network of Biodosimetry) project, 23 experienced laboratories from 16 European countries will establish a sustainable network for rapid, comprehensive and s...
متن کاملRealising the European network of biodosimetry: RENEB—status quo
Creating a sustainable network in biological and retrospective dosimetry that involves a large number of experienced laboratories throughout the European Union (EU) will significantly improve the accident and emergency response capabilities in case of a large-scale radiological emergency. A well-organised cooperative action involving EU laboratories will offer the best chance for fast and trust...
متن کاملChromosome translocations: a biomarker for retrospective biodosimetry.
We discuss here the results from our studies demonstrating that simple translocations detected by chromosome painting can be used to reconstruct radiation doses for workers exposed within the dose limits and for individuals with past exposure. To be useful, a biomarker for exposure and risk assessment should employ an end point that is highly quantitative, stable over time, and relevant to huma...
متن کاملRENEB intercomparisons applying the conventional Dicentric Chromosome Assay (DCA).
PURPOSE Two quality controlled inter-laboratory exercises were organized within the EU project 'Realizing the European Network of Biodosimetry (RENEB)' to further optimize the dicentric chromosome assay (DCA) and to identify needs for training and harmonization activities within the RENEB network. MATERIALS AND METHODS The general study design included blood shipment, sample processing, analy...
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ژورنال
عنوان ژورنال: International Journal of Radiation Biology
سال: 2016
ISSN: 0955-3002,1362-3095
DOI: 10.1080/09553002.2016.1222092